Longevity and Anti-aging Research

Epithalon - a synthetic tetrapeptide, a derivative of epithalamine – bovine pineal gland extract, is considered a potential activator of the enzyme telomerase, which protects and maintains telomere caps at the end of DNA chromosomes. Research is primarily devoted to its ability to fight against the effects of aging, as well as life extension, especially...

Thymalin is a polypeptide medication used for treatment of various diseases associated with immune dysfunction, viral and bacterial infections or regeneration issues, immunodepression, and post-chemical and radiotherapy hematogenesis depression. It has immunomodulatory and antiviral effects studied in numerous researches. Thymalin and its components...

MOTS-c is a small peptide derived from mitochondrial genome. During metabolic stress, it moves to the nucleus to regulate the expression of nuclear genes, promoting cellular balance. It is co-expressed in various tissues with mitochondria, and found in plasma, though its levels decline with age. MOTS-c, discovered by researchers at the University of...

Ipamorelin represents a synthetic pentapeptide derived from GHRP-1, which has a very potent growth hormone (GH) releasing properties with efficacy and potency comparable to GHRP-6, both in vitro and in vivo. Unlike other GH secretagogues, ipamorelin very surprisingly does not induce a significant increase in adrenocorticotropic hormone (ACTH) or cortisol...

Hexarelin, also known as Examorelin, is a synthetic GH releasing hexapeptide, which activates growth hormone secretagogue receptor (GHSR) in the brain area. It is also ghrelin analog, similarly to other peptides such as GHRP-6. Beyond GH release and neuroendocrine effects, hexarelin might have also direct cardiovascular actions and cardioprotective...

Peptide GHRP-2, also known as pralmorelin, is a synthetic hexapeptide, one of the first growth hormone secretagogues, that is known for its muscle growth increasing, ghrelin stimulating, immune system strengthening or sleep improving properties shown in numerous researches. GHRP-2 activates the release of growth hormone (GH) by binding to the growth...

Peptide GHRP-6, also known as growth hormone-releasing peptide 6, is a synthetic hexapeptide that specifically stimulates natural growth hormone release from the anterior pituitary gland by pituitary somatotrophs. It acts by binding to ghrelin receptors and mimics the effects of ghrelin – natural endogenous hormone. It has been researched for several...

Tesamorelin is one of synthetically produced growth hormone releasing hormone (GHRH) analogues, which is utilized in the treatment of HIV-associated lipodystrophy, a condition characterized by abnormal fat distribution due to antiretroviral therapy in HIV-infected patients. By activating GHRH receptors in the pituitary gland, tesamorelin stimulates the...

GHK-Cu (Copper Peptide), a naturally occurring peptide composed of three amino acids (glycyl-L-histidyl-L-lysine), has been extensively studied for its potential in wound healing, tissue regeneration, and skin rejuvenation. It stimulates blood vessel and nerve outgrowth and increases collagen, elastin, and glycosaminoglycan synthesis. GHK-Cu supports the...

Mod GRF 1-29 is a synthetic peptide identical to CJC-1295 without DAC compound. It is truncated analogue of growth hormone releasing hormone (GHRH), which was developed in 1980s from original GRF 1-29, but with purposefully prolonged half-life to ensure better therapeutical use. This modified version was shown to have similar or even the same effects as...

CJC-1295+DAC is one of modified synthetic analogues of growth hormone releasing hormone (GHRH). It acts as a growth hormone (GH) secretagogue stimulating levels of GH and insulin-like growth factor 1 (IGF-1), while preserving GH pulsatility. This stimulation in turn is the basis for its effects confirmed in various studies in animals and humans. This...