- today
HGH Frag 176-191 (AOD-9604), growth hormone fragment 176-191, or simply fragment 176-191 is a commercially synthesized hormone that is a cleavage of the natural human growth hormone produced by the pea-sized organ at the base of the brain. It is a version of the natural peptide but is cleaved from the 176 to 191 amino acids.
The identification of fragment 176-191 is credited to researchers from Monash University who discovered that the most active part of the peptide is between amino acid numbers 176 to 191. The fragment has the ability to induce the breakdown of lipids in a process called lipolysis. The active region is less than 10% of the entire human growth hormone peptide.
However, it is imperative to understand that fragment 176-191 (AOD-9604) does not have any effect on the level of insulin or insulin resistance. The principle of action of the peptide is through mimicking the natural activity of growth hormone and recent studies revealed that the peptide possesses lipid breaking and fat regulation properties. In addition, it also helps block the deposition of fats in visceral and peripheral organs.
A Brief History of Fragment 176-191 (AOD-9604)
The fragment is a biomolecular peptide that has structural and configurationally similarity to the growth hormone-releasing hormone. The peptide has shown enhanced ability to induce the production and the secretion of growth hormone from the pituitary gland.
The somatotropes are small cells that are important in the production and release of growth hormone from the pituitary gland to the target organ where it exerts its functions. One of the most important facts that we need to understand is that the production of growth hormone is in tandem with that of somatostatin. Therefore, hormone production should be enhanced for optimal functionality.
The formation of a peptide occurs when the N-terminal and the carboxyl-terminal are combined and the peptide is essential in reducing the formation and deposition of fats on peripheral organs. Inhibiting the conversion of glucose to glycogen and other fat components for the deposit when the fats are stored and energy consumption is low, then it is a problem because obesity may arise. Fragment 176-191 works through the blocking and killing of blood vessels which supply the fat cells or adipocytes. Therefore, they die off.
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