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Thymosin beta-4 promotes angiogenesis, wound healing, and hair follicle development.
New blood vessel formation is important in many physiological process, including development, wound repair, and tumor growth. In aged animals, angiogenesis is reduced resulting in poor wound healing. We have identified a novel small molecule, thymosin beta(4), that promotes angiogenesis and wound repair in both normal and aged rodents. It also promotes hair growth in normal and aged rodents. It acts by increasing angiogenesis and cell migration and is currently in clinical trials for wound repair.
The main functionality of Thymosin beta-4 hinges on the ability to up-regulate cell-building proteins like Actin. Up-regulation of Actin allows Thymosin beta-4 to promote cell migration and proliferation. This not only helps build new blood vessel pathways but also regulates inflammation directly correlated with wound healing. Its versatility even extends to its molecular structure and low molecular weight, which lends to its mobility and ability to travel long distances through tissues. This means when targeting injured areas (chronic or acute), Thymosin beta-4 has the ability to circulate the body and find those areas of injury in order to take corrective action. Added benefits of improved flexibility, reduced inflammation in tendons have been noticed, and some users report some re-grown lost hair (also reports of greyed hair darkening).
In fact, studies are being done which correlate Thymosin beta-4 with the healing of the heart, in some cases repairing ventricular hypertrophy.
Studies on Thymosin beta-4: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792846/
https://www.ncbi.nlm.nih.gov/pubmed/25412097
http://www.uk-peptides.com/thymosin-beta-4-2mg-tb500
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